Leptin Increases Hepatic Insulin Sensitivity and Protein Tyrosine Phosphatase 1B Expression
نویسندگان
چکیده
منابع مشابه
Diabetes reduces autophosphorylation of retinal insulin receptor and increases protein-tyrosine phosphatase-1B activity.
PURPOSE Protein-tyrosine phosphatase-1B (PTP1B) has been implicated in the negative regulation of insulin signaling. The expression, activity, and functional role of PTP1B in the retina are unknown. In this study, the authors examined the relationship between the retinal insulin receptor (IR) and PTP1B in normal and diabetic mouse retinas. METHODS IR and PTP1B localization was examined by imm...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 2004
ISSN: 0888-8809,1944-9917
DOI: 10.1210/me.2002-0193